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 Welcome to OnTumor.com
Booklet: Chemotherapy and You [National Cancer Institute Logo]

COPING WITH SIDE EFFECTS (2)

Blood Clotting Problem

Anticancer drugs can affect the bone marrow's ability to make platelets, the blood cells that help stop bleeding by making your blood clot. If your blood does not have enough platelets, you may bleed or bruise more easily than usual, even from a minor injury.

Be sure to let your doctor know if you have unexplained bruising, small red spots under the skin, reddish or pinkish urine, or black or bloody bowel movements. Also report any bleeding from your gums or nose. Your doctor will check your platelet count often while you are having chemotherapy. If your platelet count falls too low, the doctor may give you a transfusion to build up the count.

Here are some ways to avoid problems if your platelet count is low:

Don't take any medicine without first checking with your doctor or nurse. This includes aspirin or aspirin-free pain relievers, including acetaminophen, ibuprofen, and any other medicines you can buy without a prescription. These drugs may affect platelet function.

Mouth, Gum, and Throat Problems

Good oral care is important during cancer treatment. Anticancer drugs can cause sores in the mouth and throat. They can also make these tissues dry and irritated or cause them to bleed. In addition to being painful, mouth sores can become infected by the many germs that live in the mouth. Because infections can be hard to fight during chemotherapy and can lead to serious problems, it's important to take every possible step to prevent them.

Here are some suggestions for keeping your mouth, gums, and throat healthy:

If you develop sores in your mouth, be sure to contact your doctor or nurse because you may need medical treatment for the sores. If the sores are painful or keep you from eating, you also can try these ideas:

  • Ask your doctor if there is anything you can apply directly to the sores. You also may ask your doctor to prescribe a medicine you can use to ease the pain.
  • Eat foods cold or at room temperature. Hot and warm foods can irritate a tender mouth and throat.
  • Choose soft, soothing foods, such as ice cream, milkshakes, baby food, soft fruits (bananas and applesauce), mashed potatoes, cooked cereals, soft-boiled or scrambled eggs, cottage cheese, macaroni and cheese, custards, puddings, and gelatin. You also can puree cooked foods in the blender to make them smoother and easier to eat.
  • Avoid irritating, acidic foods, such as tomatoes, citrus fruit, and fruit juice (orange, grapefruit, and lemon); spicy or salty foods; and rough, coarse, or dry foods such as raw vegetables, granola, and toast.

If mouth dryness bothers you or makes it hard for you to eat, try these tips:

  • Ask your doctor if you should use an artificial saliva product to moisten your mouth.
  • Drink plenty of liquids.
  • Suck on ice cubes, popsicles, or sugarless hard candy. You can also chew sugarless gum.
  • Moisten dry foods with butter, margarine, gravy, sauces, or broth.
  • Dunk crisp, dry foods in mild liquids.
  • Eat soft and pureed foods like those listed above.
  • Use lip balm if your lips become dry.

Diarrhea

When chemotherapy affects the cells lining the intestine, the result can be diarrhea (loose stools). If you have diarrhea that continues for more than 24 hours, or if you have pain and cramping along with the diarrhea, call your doctor. In severe cases, the doctor may prescribe an antidiarrheal medicine. However, you should not take any over-the- counter antidiarrheal medicines without asking your doctor first.

You can also try these ideas to help control diarrhea:

Constipation

Some people who get chemotherapy become constipated because of the drugs they are taking. Others may become constipated because they are less active or less nourished than usual. Tell your doctor if you have not had a bowel movement for more than a day or two. You may need to take a laxative or stool softener or use an enema, but don't use these remedies unless you have checked with your doctor, especially if your white blood cell count is low.

You also can try these ideas to deal with constipation:

Nerve and Muscle Effects

Your nervous system affects just about all your body's organs and tissues. So it's not surprising that when chemotherapy affects the cells of the nervous system

  • as the drugs sometimes do
  • a wide range of side effects can result. For example, certain drugs can cause peripheral neuropathy, a condition that may make you feel a tingling, burning, weakness, or numbness in the hands and/or feet. Other nerve-related symptoms include loss of balance, clumsiness, difficulty picking up objects and buttoning clothing, walking problems, jaw pain, hearing loss, stomach pain, and constipation. In addition to affecting the nerves, certain anticancer drugs also can affect the muscles and make them weak, tired, or sore.
  • In some cases, nerve and muscle effects--though annoying--may not be serious. In other cases, nerve and muscle symptoms may indicate serious problems that need medical attention. Be sure to report any suspected nerve or muscle symptoms to your doctor.

Caution and common sense can help you deal with nerve and muscle problems. For example, if your fingers become numb, be very careful when grasping objects that are sharp, hot, or otherwise dangerous. If your sense of balance or muscle strength is affected, avoid falls by moving carefully, using handrails when going up or down stairs and using bathmats in the bathtub or shower. Do not wear slippery shoes.


   
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