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How is Rectal Cancer Treated: Patient Information

General Information

What is cancer of the rectum?

Cancer of the rectum, a common form of cancer, is a disease in which cancer (malignant) cells are found in the tissues of the rectum. The rectum is part of the body's digestive system. The digestive system is made up of the esophagus, stomach, and the small and large intestines. The last 6 feet of intestine is called the large bowel or colon. The last 8 to 10 inches of the colon is the rectum. The purpose of the digestive system is to remove nutrients, such as vitamins and minerals, from food and to store the waste until it passes out of the body.

A doctor should be seen if a person has a change in bowel habits or if there is any bleeding from the rectum.

A doctor will usually begin by giving the patient a rectal examination. In a rectal examination, the doctor places a gloved, greased finger into the rectum and gently feels for lumps. The doctor may then check material collected from the rectum to see if there is any blood in it.

The doctor may want to look inside the rectum and lower colon with a special instrument called a sigmoidoscope or proctosigmoidoscope. This examination, called a proctoscopy or procto examination, finds about half of all colon and rectal cancers. The doctor may also want to look inside the rectum and the entire colon (colonoscopy) with a special tool called a colonoscope. Both examinations are done in a doctor's office. Also, for both tests, patients may feel some pressure usually with no pain.

If tissue that is not normal is found, the doctor will need to cut out a small piece and look at it under the microscope to see if there are any cancer cells. This is called a biopsy. Biopsies are usually done during the proctoscopy or colonoscopy in a doctor's office.

The doctor may also perform a test called an endorectal ultrasound. This test uses sound from a probe inserted into the rectum to determine how large the tumor is, and whether it has spread.

Screening tests (such as the rectal examination, proctoscopy, and colonoscopy) may be done regularly in patients who are at higher risk to get cancer. These tests may be done in patients who are over age 50; who have a family history of cancer of the colon, rectum, or of the female organs; or who have a history of ulcerative colitis (ulcers in the lining of the large intestines).

Other tests are being developed. In patients with some forms of rectal and colon cancer, abnormal genes have been found. Genes are markers in cells associated with hereditary traits. Tests are being developed to determine who carries these abnormal genes long before cancer appears.

After treatment, blood tests (to measure amounts of carcinoembryonic antigen or CEA in the blood) and x-ray tests also may be done to see if the cancer has come back.

The prognosis (chance of recovery) and choice of treatment depend on the stage of the cancer (whether it is just in the inner lining of the rectum or if it has spread to other places) and the patient's general state of health.

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