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What You Need to Know about Esophageal Cancer [National Cancer Institute Logo]

Treatment Studies

Because esophageal cancer is so hard to control, many researchers are looking for more effective treatments. They are also exploring ways to reduce side effects. When laboratory research shows that a new method has promise, it is used to treat cancer patients in clinical trials. These trials are designed to answer scientific questions and to find out whether the new approach is both safe and effective. Patients who take part in clinical trials make an important contribution to medical science and may have the first chance to benefit from improved treatment methods.

Many clinical trials of new treatments for esophageal cancer are under way. Doctors are studying new ways of combining various types of treatment. They are also trying new anticancer drugs and drug combinations, as well as drugs that make cancer cells more sensitive to radiation. Another method under study is photodynamic Ktherapy, the use of laser light and drugs that make the cancer cells sensitive to light so the laser can destroy them. Researchers are also exploring biological therapy, treatment intended to help the body's immune system fight cancer more effectively.

Patients with esophageal cancer who are interested in taking part in a trial should talk with their doctor. They may want to read Taking Part in Clinical Trials: What Cancer Patients Need To Know, a booklet that explains the possible benefits and risks of treatment studies.

One way to learn about clinical trials is through PDQ, a computerized resource of cancer treatment information. Developed by the National Cancer Institute, PDQ contains an up-to-date list of trials all over the country. The CIS, at 1-800-4-CANCER, can provide PDQ information to doctors, patients, and the public.

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