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 Welcome to OnTumor.com
How is Pancreatic Cancer Treated [National Cancer Institute Logo]

Treatment by stage

     Treatment of cancer of the pancreas depends on the stage of the disease, and the patient's age and overall condition.

     Standard treatment may be considered because of its effectiveness in patients in past studies, or participation in a clinical trial may be considered. Most patients with cancer of the pancreas are not cured with standard therapy and some standard treatments may have more side effects than are desired. For these reasons, clinical trials are designed to find better ways to treat cancer patients and are based on the most up-to-date information. Clinical trials are ongoing in most parts of the country for all stages of cancer of the pancreas. To learn more about clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237); TTY at 1-800-332-8615.

Stage I Pancreatic Cancer

Treatment may be one of the following:

  1. Surgery to remove the head of the pancreas, part of the small intestine, and some of the surrounding tissues (Whipple procedure).
  2. Surgery to remove the entire pancreas and the organs around it (total pancreatectomy).
  3. Surgery to remove the body and tail of the pancreas (distal pancreatectomy).
  4. Surgery followed by chemotherapy and radiation therapy.
  5. Clinical trials of radiation therapy with or without chemotherapy given before, during, or after surgery.

Stage II Pancreatic Cancer

Treatment may be one of the following:

  1. Surgery to remove all or part of the pancreas with or without chemotherapy and radiation therapy.
  2. External radiation therapy with or without chemotherapy.
  3. Surgery or other treatments to reduce symptoms.
  4. Clinical trials of radiation therapy and chemotherapy given before surgery.
  5. Clinical trials of radiation therapy plus drugs to make cancer cells more sensitive to radiation (radiosensitizers).
  6. Clinical trials of chemotherapy.
  7. Clinical trials of radiation therapy given during surgery with or without internal radiation therapy.

Stage III Pancreatic Cancer

Treatment may be one of the following:

  1. Surgery to remove all or part of the pancreas with or without chemotherapy and radiation therapy.
  2. External radiation therapy with or without chemotherapy.
  3. Surgery or other treatments to reduce symptoms.
  4. Clinical trials of radiation therapy and chemotherapy given before surgery.
  5. Clinical trials of surgery plus radiation therapy plus drugs to make cancer cells more sensitive to radiation (radiosensitizers).
  6. Clinical trials of chemotherapy.
  7. Clinical trials of radiation therapy given during surgery, with or without internal radiation therapy.

Stage IVA Pancreatic Cancer

Treatment may be one of the following:

  1. Surgery to remove all or part of the pancreas with or without chemotherapy and radiation therapy.
  2. External radiation therapy with or without chemotherapy.
  3. Surgery or other treatments to reduce symptoms.
  4. Clinical trials of radiation therapy and chemotherapy given before surgery.
  5. Clinical trials of surgery plus radiation therapy plus drugs to make cancer cells more sensitive to radiation (radiosensitizers).
  6. Clinical trials of chemotherapy.
  7. Clinical trials of radiation therapy given during surgery, with or without internal radiation therapy.

Stage IVB Pancreatic Cancer

Treatment may be one of the following:

  1. Chemotherapy.
  2. Treatments for pain and other symptoms.
  3. Surgery or other treatments to reduce symptoms.
  4. Clinical trials of chemotherapy or biological therapy.

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