Stage Information

A hysterectomy is required to determine the degree of myometrial invasion. The following surgical staging has been adopted by the International Federation of Gynecology and Obstetrics (FIGO) and by the American Joint Committee on Cancer (AJCC):1-3

Stage I
Stage I endometrial cancer is carcinoma confined to the corpus uteri.
stage IA: tumor limited to endometrium
stage IB: invasion to less than one half of the myometrium
stage IC: invasion to greater than one half of the myometrium

Stage II
Stage II endometrial cancer involves the corpus and the cervix, but has not extended outside the uterus.
stage IIA: endocervical glandular involvement only
stage IIB: cervical stromal invasion

Stage III
Stage III endometrial cancer extends outside of the uterus but is confined to the true pelvis.
stage IIIA: tumor invades serosa and/or adnexa and/or positive peritoneal
cytology
stage IIIB: vaginal metastases
stage IIIC: metastases to pelvic and/or para-aortic lymph nodes

Stage IV
Stage IV endometrial cancer involves the bladder or bowel mucosa or has
metastasized to distant sites.
stage IVA: tumor invasion of bladder and/or bowel mucosa
stage IVB: distant metastases, including intra-abdominal and/or inguinal
lymph nodes

Endometrial cancer can be grouped with regard to the degree of differentiation of the adenocarcinoma, as follows:

G1: 5% or less of a nonsquamous or nonmorular solid growth pattern

G2: 6% to 50% of a nonsquamous or nonmorular solid growth pattern

G3: more than 50% of a nonsquamous or nonmorular solid growth pattern

FIGO staging for endometrial cancer:
  Stage IA G123: tumor limited to endometrium
  Stage IB G123: invasion to less than one half the myometrium
  Stage IC G123: invasion to more than one half the myometrium
  Stage IIA G123: endocervical glandular involvement only
  Stage IIB G123: cervical stromal invasion
  Stage IIIA G123:tumor invades serosa and/or adnexa, and/or positive
peritoneal cytology
  Stage IIIB G123:vaginal metastases
  Stage IIIC G123:metastases of pelvic and/or para-aortic lymph nodes
  Stage IVA G123: tumor invasion of bladder and/or bowel mucosa
  Stage IVB: distant metastases including intra-abdominal and/or inguinal
lymph nodes

NEXT >>

Index of the Booklet